The Uchucklesaht First Nation is a First Nation based on the west coast of Vancouver Island in British Columbia, Canada.

Ugashik Village is located in the Lake and Peninsula Borough of Alaska near Pilot Point.

The Ulkatcho First Nation is a Dakelh First Nations band in British Columbia, with offices located around Anahim Lake.

Ulukhaktok, formerly known as Holman, is a small hamlet on the west coast of Victoria Island, in the Inuvik Region of the Northwest Territories, Canada.

Umkumiut Native Village is located in the Bethel Census Area of Alaska near the city of Nightmute.

United Auburn Indian Community of the Auburn Rancheria of California is mostly Miwok Indians located in the Sierra Nevada foothills near Auburn, in Placer County, California.

United Keetoowah Band of Cherokee Indians in Oklahoma are headquarted in Tahiequah, Oklahoma.

The Mattaponi tribe is one of only two Virginia Indian tribes in the Commonwealth of Virginia that owns reservation land near Westpoint.

The Upper Nicola Band is a First Nation in the Canadian province of British Columbia, located near the town of Merritt in the Nicola Country at Douglas Lake.

The Upper Similkameen Indian Band is a First Nation in British Columbia, whose head offices are located in the town of Hedley in the Similkameen Country.

Upper Sioux Community, Minnesota is located in Minnesota with three Dakota Bands of the Mdewakanton tribe.

Upper Skagit Indian Tribe is located in Skagit County, Washington.

Ute Indian Tribe of the Uintah & Ouray Reservation have a number of bands that are located in Utah.

Ute Mountain Ute Tribe is located in Towaoc, Colorado.

Utu Utu Gwaitu Paiute Tribe of the Benton Paiute Reservation is located in Mono County, California.